ColoScapeTM Colorectal Cancer Mutation Detection Test

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What is Colorectal Cancer?

  1. Most colorectal cancers (CRC) begin as a growth, or lesion, in
    the tissue that lines the inner surface of the colon or rectum.
  2. Lesions may appear as raised polyps, (a growth that protrudes
    from a mucous membrane) that may be attached to the inner
    surface of the colon or rectum with or without a stalk
  3. Colorectal polyps are common in people older than 50 years of age, and most do not become cancer.
    However, a certain type of polyp known as an adenoma (tumor) most likely to become a cancer.
  4. Most CRCs develop from adenomas, among which “advanced” adenomas are considered to be the clinically relevant precursors of CRC.

ColoScapeTM Colorectal Cancer Mutation Detection Test

A simple blood test

  • No need to fast
  • No dietary restrictions before the test
  • Easy and Convenient to your schedule
  • No bowel prep
  • No sedation
  • Fast Turn-Around-Time  (4-7 days from  specimen receipt in the lab)

  • Highly Sensitive, Highly Accurate blood test
  • Liquid Biopsy Detects 61 Mutations & 7 Methylation Markers associated with CRC

ColoscapeTM  Colorectal Cancer Test

Sensitivity

Specificity

Colorectal Cancer Mutation Detection  93%  93% to 100%
Precancerous Adenomas 62% 95.2%

  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0244332

 

Uses novel XNA technology that detects high level of sensitivity and specificity for precancerous lesions before they progress into CRC. Xenonucleic acids, are innovative new nucleic acid molecular oligomers that hybridize with target DNA sequences and can be employed as molecular clamps in quantitative real-time polymerase chain reactions (qPCR). The XNA tightly bind to the wild-type sequence but loosely to the mutant sequences, thereby allowing mutant sequences to be amplified in a PCR reaction while blocking wild-type sequence amplification with utmost precision. Click Here To Learn More

XNA Techmology

ColoScape™ is a laboratory developed test used to detect genetic mutations associated with Colorectal Cancer.

 

  1. This test is not a replacement for Colonoscopy. This is intended as complementary test to the recommended screening method.
  2. For Patients Results that are “Detected” you are advised to seek guidance of your healthcare provider or doctor for further evaluation for Con Colonoscopy.
    For Patients with “Not Detected” results should continue to follow the recommended guideline for colorectal screening.
  3. DiaCarta Clinical Laboratories developed ColoScape and hold its certificate under the Clinical Laboratory
    Improvement Amendments of 1988 (CLIA) as qualified to perform high complexity clinical testing. This test has not been cleared or approved by the US FDA

Analytical sensitivity in FFPE (QClamp® KRAS Mutation Detection Test) powered by XNA technology

Analytical sensitivity in plasma (QClamp® KRAS Mutation Detection Test) powered by XNA technology

Getting your ColoScape test completed is easy!

Step 1. Click any ‘Order Test Kit’ button on the website and ‘Add to Cart’.

1.a. Add ‘Mobile Collection’ (if so desired).

Step 2. Sample collection options below. 

Step 3. When your test kit arrives, return to our website to register the kit code to access your results when they are ready. You will be notified by email when your test result is available.

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